Paradoxical hyperfixation of hexamethylpropyleneamine oxime in cerebral infarction.

Paradoxical hyperfixation of HMPAO in cerebral infarction.

Spurious hyperfixation of hexamethylpropyleneamine oxime in acute embolic stroke.

A 71-year-old man with atrial fibrillation suddenly had an embolism in the right middle cerebral artery. Single-photon emission CT was performed 4 hours after the onset of stroke and revealed markedly elevated 99mTc-hexamethylpropyleneamine oxime (HMPAO) uptake in the right frontotemporoparietal region. This area of HMPAO hyperfixation corresponded to the area of infarction, as determined by CT...

Hyperfixation of HMPAO in subacute ischemic stroke leading to spuriously high estimates of cerebral blood flow by SPECT.

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A spurious description of hyperfixation of HMPAO.

Evaluation of ""Tc-Hexamethylpropyleneamine Oxime Cerebral Blood Flow Mapping After Acute Focal Ischemia in Rats

Although the blood flow tracer hexamethylpropyleneamine oxime is now widely used for cerebral blood flow mapping using single-photon emission computed tomography, its uptake into acutely ischemic brain has not been well studied. We performed a double-label autoradiographic study in which "Tc-hexamethylpropyleneamine oxime uptake was compared with [C]iodoantipyrine-derived cerebral blood flow 0....